Searchable abstracts of presentations at key conferences in endocrinology

ea0056oc3.3 | New insights in bone disorders | ECE2018

[18F]-FDG PET/CT imaging: A tool to reveal the metabolic functions of bone marrow adipose tissue

Suchacki Karla , Tavares Adriana , Sinton Matthew , Alcaide Carlos , Morton Nicholas , Cawthorn William

Introduction: White adipose tissue (WAT) and brown adipose tissue (BAT) are key regulators of systemic metabolic function. Bone marrow adipose tissue (BMAT) accounts for 10% of total adipose mass in healthy humans and therefore can be considered a third major adipose subtype. However, it is unclear if BMAT contributes to systemic energy homeostasis.Objectives: Assess [18F]-Fluorodeoxyglucose (FDG) uptake into bone and the marrow cavity (MC) fo...

ea0041oc7.1 | Cardiovascular endocrinology | ECE2016

Lipoprotein lipase DNA methylation: cause or consequence of metabolic disorders

Castellano-Castillo Daniel , Moreno-Indias Isabel , Queipo-Ortuno Maria Isabel , Fernandez-Garcia Jose Carlos , Alcaide-Torres Juan , Tinahones Francisco , Cardona-Diaz Fernando

Introduction: DNA methylation is one of the epigenetic mechanisms existing to regulate gene expression. It is believed that methylation of DNA is susceptible of change by environmental and nutritional factors. Thus, epigenetics provides a mechanism which may explain the etiology of some metabolic disorders and obesity.Aim: The aim of this study is to analyze the DNA methylation level of several lipoprotein lipase (LPL)-promoter-CpG island in human viscer...